BDPI
Based on 1 Customer Validation
BDPI is the a BODIPY derivative. BDPI reveals a high O2 quantum yield and exhibits phototoxicity that inhibits HeLa with an IC50 of 0.6 µg/mL. BDPI nanoarticles can be taken up by HeLa, producing fluorescence signals in the cells, and can be used as cell imaging agent. BDPI nanoarticles exhibit antitumor efficacy in mouse models.
For research use only. We do not sell to patients.
- CAS No.: 1083009-44-2
- Formula: C19H17BF2I2N2
- Molecular Weight:575.97
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEp-2 | IC50 |
>400 μM
Compound: 1a
|
Dark toxicity in human Hep2 cells after 24 hrs by Cell Titre Blue assay
Dark toxicity in human Hep2 cells after 24 hrs by Cell Titre Blue assay
|
[PMID: 23928070] |
| HEp-2 | IC50 |
27 μM
Compound: 1a
|
Phototoxicity in human Hep2 cells incubated for 24 hrs followed by 1.5 J/cm'2 light irradiation for 20 mins measured after 24 hrs by Cell Titre Blue assay
Phototoxicity in human Hep2 cells incubated for 24 hrs followed by 1.5 J/cm'2 light irradiation for 20 mins measured after 24 hrs by Cell Titre Blue assay
|
[PMID: 23928070] |
Chemical Information
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CAS No. 1083009-44-2
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Appearance Solid
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Molecular Weight 575.97
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Formula C19H17BF2I2N2
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SMILES
CC(C(I)=C1C)=C(N1[B-]2(F)F)C(C3=CC=CC=C3)=C4[N+]2=C(C)C(I)=C4C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)