N-Iodosuccinimide
Based on 1 Customer Validation
N-Iodosuccinimide is a biological material or organic compound that can be used in life science research.
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 516-12-1
- Formula: C4H4INO2
- Molecular Weight:224.98
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Storage:
4°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 516-12-1
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Appearance Solid
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Molecular Weight 224.98
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Formula C4H4INO2
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SMILES
O=C(CC1)N(I)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
Methanol : ≥ 200 mg/mL (888.97 mM)
DMSO : 100 mg/mL (444.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (22.22 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * The compound is unstable in solutions, freshly prepared is recommended.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (762 KB)
- English - EN (762 KB)
- Français - FR (762 KB)
- Deutsch - DE (762 KB)
- Norwegian - NO (762 KB)
- Español - ES (762 KB)
- Swedish - SV (762 KB)
- Italian - IT (762 KB)
- Korean - KR (762 KB)
- Portuguese - PT (762 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Methanol | 1 mM | 4.4448 mL | 22.2242 mL | 44.4484 mL | 111.1210 mL |
| 5 mM | 0.8890 mL | 4.4448 mL | 8.8897 mL | 22.2242 mL | |
| 10 mM | 0.4445 mL | 2.2224 mL | 4.4448 mL | 11.1121 mL | |
| 15 mM | 0.2963 mL | 1.4816 mL | 2.9632 mL | 7.4081 mL | |
| 20 mM | 0.2222 mL | 1.1112 mL | 2.2224 mL | 5.5560 mL | |
| 25 mM | 0.1778 mL | 0.8890 mL | 1.7779 mL | 4.4448 mL | |
| 30 mM | 0.1482 mL | 0.7408 mL | 1.4816 mL | 3.7040 mL | |
| 40 mM | 0.1111 mL | 0.5556 mL | 1.1112 mL | 2.7780 mL | |
| 50 mM | 0.0889 mL | 0.4445 mL | 0.8890 mL | 2.2224 mL | |
| 60 mM | 0.0741 mL | 0.3704 mL | 0.7408 mL | 1.8520 mL | |
| 80 mM | 0.0556 mL | 0.2778 mL | 0.5556 mL | 1.3890 mL | |
| 100 mM | 0.0444 mL | 0.2222 mL | 0.4445 mL | 1.1112 mL |
N-Iodosuccinimide Related Classifications
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