Nec-3a
Nec-3a is a Necrostatin-3 analogue. Nec-3a is a RIP1 inhibitor (IC50: 0.44 μM). Nec-3a inhibits the autophosphorylation activity of the RIP1 kinase domain.
For research use only. We do not sell to patients.
- CAS No.: 1504558-72-8
- Formula: C21H18F4N2O4
- Molecular Weight:438.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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RIPK1 0.44 μM (IC50) |
Chemical Information
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CAS No. 1504558-72-8
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Molecular Weight 438.37
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Formula C21H18F4N2O4
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SMILES
COC1=CC=C2CC[C@H]3[C@@H](C4=CC=C(C(F)=C4)OC(F)(F)F)N(C(CO)=O)N=C3C2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)