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Cat. No.: HY-126412

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Neochamaejasmine A

Neochamaejasmine A is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L.. Neochamaejasmine A inhibits proliferation, induces cell cycle arrest and apoptosis in tumor cells. Neochamaejasmine A can be used in the research of cancers such as prostate cancer, hepatoma cancer.

For research use only. We do not sell to patients.

CAS No.: 90411-13-5
Formula: C₃₀H₂₂O₁₀
Molecular Weight:542.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Neochamaejasmine A Chemical Structure

CAS No.: 90411-13-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
L929	IC₅₀	90 μg/mL Compound: 1	Cytotoxicity against mouse L929 cells after 48 hrs by MTT assay Cytotoxicity against mouse L929 cells after 48 hrs by MTT assay	[PMID: 18380477]
LNCaP	IC₅₀	12.5 μg/mL Compound: 1	Cytotoxicity against human LNCaP cells after 48 hrs by MTT assay Cytotoxicity against human LNCaP cells after 48 hrs by MTT assay	[PMID: 18380477]
SW-620	IC₅₀	25.1 μg/mL Compound: 1	Cytotoxicity against human SW620 cells after 48 hrs by MTT assay Cytotoxicity against human SW620 cells after 48 hrs by MTT assay	[PMID: 18380477]

Chemical Information

CAS No. 90411-13-5
Molecular Weight 542.49
Formula C₃₀H₂₂O₁₀
SMILES

O=C1[C@]([C@@]2([H])[C@@H](C3=CC=C(C=C3)O)OC4=CC(O)=CC(O)=C4C2=O)([H])[C@@H](C5=CC=C(C=C5)O)OC6=CC(O)=CC(O)=C61
Structure Classification
- Flavonoids
- Biflavones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu WK, et al. Involvement of p21 and FasL in induction of cell cycle arrest and apoptosis by neochamaejasmin A in human prostate LNCaP cancer cells. J Nat Prod. 2008 May;71(5):842-6. [Content Brief]

[2]. Ding Y, et al. Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway. Oxid Med Cell Longev. 2020 Jan 20;2020:3237150. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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