NHE-1-IN-2
Based on 1 Customer Validation
NHE-1-IN-2 (compound 7g) is a potent NHE-1 inhibitor with an IC50 of 0.78 μM. NHE-1-IN-2 alleviates left ventricular systolic dysfunction in mice model of heart failure.
For research use only. We do not sell to patients.
- Purity: 99.57%
- CAS No.: 3107091-05-1
- Formula: C23H20ClN3O3
- Molecular Weight:421.88
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Membrane Transporter/Ion Channel Compound Library
HY-L011
-
Membrane Protein-targeted Compound Library
HY-L149
-
Membrane Receptor-targeted Compound Library
HY-L150
-
MCE Bioactive Compound Library
HY-L001V
-
High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
-
CAS No. 3107091-05-1
-
Appearance Solid
-
Molecular Weight 421.88
-
Formula C23H20ClN3O3
-
Color White to off-white
-
SMILES
O=C(C1=CC=C(C2=CC=C(Cl)C(C(C3=CC=C(OCC)C=C3)=O)=C2)C=C1)NC(N)=N
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 87.5 mg/mL (207.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (266 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3703 mL | 11.8517 mL | 23.7034 mL | 59.2586 mL |
| 5 mM | 0.4741 mL | 2.3703 mL | 4.7407 mL | 11.8517 mL | |
| 10 mM | 0.2370 mL | 1.1852 mL | 2.3703 mL | 5.9259 mL | |
| 15 mM | 0.1580 mL | 0.7901 mL | 1.5802 mL | 3.9506 mL | |
| 20 mM | 0.1185 mL | 0.5926 mL | 1.1852 mL | 2.9629 mL | |
| 25 mM | 0.0948 mL | 0.4741 mL | 0.9481 mL | 2.3703 mL | |
| 30 mM | 0.0790 mL | 0.3951 mL | 0.7901 mL | 1.9753 mL | |
| 40 mM | 0.0593 mL | 0.2963 mL | 0.5926 mL | 1.4815 mL | |
| 50 mM | 0.0474 mL | 0.2370 mL | 0.4741 mL | 1.1852 mL | |
| 60 mM | 0.0395 mL | 0.1975 mL | 0.3951 mL | 0.9876 mL | |
| 80 mM | 0.0296 mL | 0.1481 mL | 0.2963 mL | 0.7407 mL | |
| 100 mM | 0.0237 mL | 0.1185 mL | 0.2370 mL | 0.5926 mL |
NHE-1-IN-2 Related Classifications
HY-173517 Related Classifications
Powered by Bioz