EG31
EG31 is an EGFR inhibitor. EG31 effectively inhibits the proliferation of triple-negative breast cancer (TNBC) cells (GI50 values of MDA-MB-231 and Hs578T cells are 498.90 nM and 740.73 nM, respectively) and induces apoptosis by inhibiting the EGFR signaling pathway. EG31 still maintains antiproliferative activity against 5-fluorouracil (5-FU)-resistant TNBC cells (GI50: 519.5 nM). EG31 can be used to study TNBC resistance.
For research use only. We do not sell to patients.
- CAS No.: 360760-58-3
- Formula: C30H13Br2N3O6
- Molecular Weight:671.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 360760-58-3
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Molecular Weight 671.25
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Formula C30H13Br2N3O6
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SMILES
O=C1OC(C2=CC(N3C(C4=C(C3=O)C=CC=C4)=O)=CC(C5=NC6=C(C(O5)=O)C=C(C=C6)Br)=C2)=NC7=CC=C(C=C17)Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EG31 Related Classifications
HY-172966 Related Classifications
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