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Indusatumab

(Synonyms: 5F9 Monoclonal antibody; TAK-164 Antibody)
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Based on 1 Customer Validation

Indusatumab (5F9 Monoclonal antibody) is a monoclonal antibody against human GUCY2C (Guanylate cyclase 2C). Indusatumab fails to bind to granulocytes or erythrocytes. Indusatumab can be used to synthesize ADCs, such as Indusatumab vedotin (HY-P99662). Indusatumab can be used in cancer research.

For research use only. We do not sell to patients.

  • Purity : ≥99.0%
  • CAS No.: 1497400-26-6
  • Molecular Weight:145.206 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Indusatumab
  • Experimental Validation Results for Indusatumab
  • Experimental Validation Results for Indusatumab
  • Experimental Validation Results for Indusatumab
  • Indusatumab Chemical Structure
    Indusatumab Chemical Structure
CAS No.: 1497400-26-6
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Indusatumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Indusatumab on AHC2 biosensor, can bind GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, His-Avi, HY-P77944) with an affinity constant of 2.157E-08 M as determined in BLI assay.

  • 1/16

    Immobilized Hu-GUCY2C-his can bind Indusatumab. The EC50 for this effect is 4.769 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 SiHa cells labeling GUCY2C with Indusatumab (HY-P99232, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Indusatumab Chemical Structure
    1/16
  • Indusatumab
  • Loaded Indusatumab on AHC2 biosensor, can bind GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, His-Avi, HY-P77944) with an affinity constant of 2.157E-08 M as determined in BLI assay.
  • Immobilized Hu-GUCY2C-his can bind Indusatumab. The EC50 for this effect is 4.769 ng/mL.
  • Flow cytometric analysis of 1X106 SiHa cells labeling GUCY2C with Indusatumab (HY-P99232, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).