Refinicopan
Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM. Refinicopan inhibits hemolysis of rabbit red blood cells. Refinicopan can be used to study diseases mediated by complement factor D.
For research use only. We do not sell to patients.
- CAS No.: 2922808-66-8
- Formula: C29H32N2O3
- Molecular Weight:456.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Complement factor D 10 nM (IC50) |
Refinicopan (Compound 001) inhibits hemolysis of rabbit red blood cells in a cell-based assay with an IC50 of 41 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2922808-66-8
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Molecular Weight 456.58
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Formula C29H32N2O3
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SMILES
NCC1=CC=CC(C2=CC(N3CCC4(CC3)CC4)=CC(COC5=C(C=CC=C5)CC(O)=O)=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)