ZM640
ZM640 is a NLRP3 inhibitor. ZM640 enhances IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. ZM640 shows low cytotoxicity.
For research use only. We do not sell to patients.
- Formula: C28H36F3NO8S
- Molecular Weight:603.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | CC50 |
>100 μM
Compound: ZM640
|
Cytotoxicity against human THP-1 cells by CCK-8 method
Cytotoxicity against human THP-1 cells by CCK-8 method
|
[PMID: 38244941] |
Chemical Information
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Molecular Weight 603.65
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Formula C28H36F3NO8S
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SMILES
O=S(NCC[C@H]1[C@H](CC2)[C@@H](O)[C@@]([C@@]3(O)[C@@H](O)[C@]4([H])C(C)(C)CC5)(C1=O)[C@]2([H])[C@]4(CO3)[C@H]5O)(C6=CC=C(C=C6)C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)