NLRP3-IN-21
Based on 1 publication(s) in Google Scholar
NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.97%
- CAS. Nr.: 2956791-61-8
- Formel: C20H13Cl2F3N6O2S
- Molecular Weight:529.32
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Immunology/Inflammation Compound Library
HY-L007
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NF-κB Signaling Compound Library
HY-L014
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Antioxidant Compound Library
HY-L037
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Oxygen Sensing Compound Library
HY-L045
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Pyroptosis Compound Library
HY-L059
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Antidepressant Compound Library
HY-L108
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Membrane Receptor-targeted Compound Library
HY-L150
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Autoimmune Disease Compound Library
HY-L156
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Inflammasomes related Compound Library
HY-L175
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Radioprotector Library
HY-L178
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MCE Bioactive Compound Library
HY-L001V
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High-Throughput Bioactive Compound Library
HY-L205
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Pattern Recognition Receptors Library
HY-L237
Publications Citing Use of MedChemExpress (MCE) NLRP3-IN-21
More
Biologische Aktivität
Chemical Information
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CAS. Nr. 2956791-61-8
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Appearance Solid
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Molecular Weight 529.32
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Formel C20H13Cl2F3N6O2S
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Color White to off-white
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SMILES
O=C1N(N=C(N2C1=CC3=C2C=C(S3)Cl)C(C)C)CC4=NN=C(O4)C5=CC=C(N=C5Cl)C(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
Embryo-Derived Cathepsin B Promotes Implantation and Decidualization by Activating Pyroptosis. [Abstract]2024 Nov;11(43):e2402299. PMID: 39316370
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (188.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8892 mL | 9.4461 mL | 18.8922 mL | 47.2304 mL |
| 5 mM | 0.3778 mL | 1.8892 mL | 3.7784 mL | 9.4461 mL | |
| 10 mM | 0.1889 mL | 0.9446 mL | 1.8892 mL | 4.7230 mL | |
| 15 mM | 0.1259 mL | 0.6297 mL | 1.2595 mL | 3.1487 mL | |
| 20 mM | 0.0945 mL | 0.4723 mL | 0.9446 mL | 2.3615 mL | |
| 25 mM | 0.0756 mL | 0.3778 mL | 0.7557 mL | 1.8892 mL | |
| 30 mM | 0.0630 mL | 0.3149 mL | 0.6297 mL | 1.5743 mL | |
| 40 mM | 0.0472 mL | 0.2362 mL | 0.4723 mL | 1.1808 mL | |
| 50 mM | 0.0378 mL | 0.1889 mL | 0.3778 mL | 0.9446 mL | |
| 60 mM | 0.0315 mL | 0.1574 mL | 0.3149 mL | 0.7872 mL | |
| 80 mM | 0.0236 mL | 0.1181 mL | 0.2362 mL | 0.5904 mL | |
| 100 mM | 0.0189 mL | 0.0945 mL | 0.1889 mL | 0.4723 mL |
NLRP3-IN-21 Related Classifications
HY-149604 Related Classifications
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