NLRP3-IN-92
NLRP3-IN-92 is a NLRP3 inflammasome inhibitor. NLRP3-IN-92 can be used for the research of immune diseases and inflammatory diseases.
For research use only. We do not sell to patients.
- CAS No.: 2557366-30-8
- Formula: C19H23F3N4O
- Molecular Weight:380.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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NLRP3 |
NLRP3-IN-92 (((S)-2-(6-((1-Ethylpiperidin-3-yl) amino) pyridazin-3-yl)-3-methyl-5-(trifluoromethyl) phenol)) is an inhibitor of the NLRP3 inflammasome. NLRP3 is a cytoplasmic pattern recognition receptor that assembles inflammasomes to activate caspase-1, cleave IL-1β/IL-18 and mediate pyroptosis, serving as a core inflammatory sensor for bacteria, toxins and damage signals[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2557366-30-8
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Molecular Weight 380.42
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Formula C19H23F3N4O
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SMILES
CC1=C(C(O)=CC(C(F)(F)F)=C1)C2=CC=C(N[C@@H]3CN(CC)CCC3)N=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)