1. Immunology/Inflammation
  2. NO Synthase
  3. NOS-IN-1

NOS-IN-1 

Cat. No.: HY-138564
Handling Instructions

NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively.

For research use only. We do not sell to patients.

NOS-IN-1 Chemical Structure

NOS-IN-1 Chemical Structure

CAS No. : 165383-72-2

Size Price Stock
10 mg USD 320 Ask For Quote & Lead Time

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively[1].

IC50 & Target

IC50: 0.1 μM (hiNOS), 1.1 μM (heNOS), and 0.2 μM (hnNOS)[1]

In Vivo

Following oral administration, NOS-IN-1 (compound 3; 10 mg/kg) decreases serum nitrite/nitrate levels in an in vivo rat endotoxin assay[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

172.22

Formula

C₈H₁₆N₂O₂

CAS No.
SMILES

NC1=NCCC(C)C1.CC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

NOS-IN-1NO SynthaseNitric oxide synthasesNOSiNOSeNOSnNOSoralnitritenitrateInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
NOS-IN-1
Cat. No.:
HY-138564
Quantity:
MCE Japan Authorized Agent: