NOS-IN-1
Based on 1 Customer Validation
NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively.
For research use only. We do not sell to patients.
- Purity: 98.18%
- CAS No.: 165383-72-2
- Formula: C8H16N2O2
- Molecular Weight:172.22
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.1 μM (hiNOS), 1.1 μM (heNOS), and 0.2 μM (hnNOS)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 165383-72-2
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Appearance Solid
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Molecular Weight 172.22
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Formula C8H16N2O2
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Color White to off-white
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SMILES
NC1=NCCC(C)C1.CC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 6.5 mg/mL (37.74 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.8065 mL | 29.0326 mL | 58.0653 mL | 145.1632 mL |
| 5 mM | 1.1613 mL | 5.8065 mL | 11.6131 mL | 29.0326 mL | |
| 10 mM | 0.5807 mL | 2.9033 mL | 5.8065 mL | 14.5163 mL | |
| 15 mM | 0.3871 mL | 1.9355 mL | 3.8710 mL | 9.6775 mL | |
| 20 mM | 0.2903 mL | 1.4516 mL | 2.9033 mL | 7.2582 mL | |
| 25 mM | 0.2323 mL | 1.1613 mL | 2.3226 mL | 5.8065 mL | |
| 30 mM | 0.1936 mL | 0.9678 mL | 1.9355 mL | 4.8388 mL |
NOS-IN-1 Related Classifications
HY-138564 Related Classifications
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