NR2E3 agonist 1
Based on 1 Customer Validation
NR2E3 agonist 1 (Compound 11a) is a small molecule agonist of the photoreceptor-specific nuclear receptor (NR2E3) with an EC50 value of less than 200 nM. NR2E3 agonist 1 can be used in retinitis pigmentosa research.
For research use only. We do not sell to patients.
- Purity: 99.48%
- CAS No.: 911211-69-3
- Formula: C24H19ClN4O2
- Molecular Weight:430.89
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
35 nM
Compound: 11a
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Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells
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[PMID: 16879962] |
Chemical Information
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CAS No. 911211-69-3
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Appearance Solid
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Molecular Weight 430.89
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Formula C24H19ClN4O2
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Color White to off-white
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SMILES
O=C(C1CC1)NC2=CC=C(NC(C3=CC=C(NC(C4=CC=CC=C4Cl)=O)C=C3)=N5)C5=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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