Nrf2 activator-11
Nrf2 activator-11 (compound M11) is a Nrf2 activator with blood-brain permeability. Nrf2 activator-11 has anti-oxidation, anti-inflammation, anti-ferroptosis and anti-apoptosis. Nrf2 activator-11 can be used to study cerebral ischemia-reperfusion (CI/R) injury models.
For research use only. We do not sell to patients.
- CAS No.: 3069351-39-6
- Formula: C20H23N3O2
- Molecular Weight:337.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
>100 μM
Compound: M11
|
Cytotoxicity against mouse BV-2 cells assessed as cell viability incubated for 24 hrs by CCK-8 method
Cytotoxicity against mouse BV-2 cells assessed as cell viability incubated for 24 hrs by CCK-8 method
|
[PMID: 39216381] |
| HT-22 | IC50 |
>100 μM
Compound: M11
|
Cytotoxicity against mouse HT-22 cells assessed as cell viability incubated for 24 hrs by CCK-8 method
Cytotoxicity against mouse HT-22 cells assessed as cell viability incubated for 24 hrs by CCK-8 method
|
[PMID: 39216381] |
Chemical Information
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CAS No. 3069351-39-6
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Molecular Weight 337.42
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Formula C20H23N3O2
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SMILES
O=C(C1=C(O)C=C(C)C=C1)NCCC2=CNC3=CC=C(N(C)C)C=C32
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)