NSC850143
NSC850143 is an antiproliferative agent. NSC850143 induces antiproliferative and cytotoxic effects in aggressive tumor cells. NSC850143 can be used in the research of cancers such as leukemia, non-small cell lung cancer, colon cancer, central nervous system cancer, melanoma, ovarian cancer, renal cancer, prostate cancer and breast cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C26H23N5O4S
- Molecular Weight:501.56
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vitro
NSC850143 (10 μM; 10-8-10-4 M) exhibits potent, broad antiproliferative activity against the NCI-60 human tumor cell line panel, with a mean GI50 of 0.98 μM, and shows strong cytotoxicity against leukemia, NSCLC, melanoma, ovarian, renal, and breast cancer cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 501.56
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Formel C26H23N5O4S
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SMILES
O=C(C(S1)=C(NC(C2=CC=C(OC)C=C2)=O)C3=C1C4=CC(NCC5=CNC=N5)=CC=C4N=C3)OCC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)