NSC850143
NSC850143 is an antiproliferative agent. NSC850143 induces antiproliferative and cytotoxic effects in aggressive tumor cells. NSC850143 can be used in the research of cancers such as leukemia, non-small cell lung cancer, colon cancer, central nervous system cancer, melanoma, ovarian cancer, renal cancer, prostate cancer and breast cancer.
For research use only. We do not sell to patients.
- Formula: C26H23N5O4S
- Molecular Weight:501.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
NSC850143 (10 μM; 10-8-10-4 M) exhibits potent, broad antiproliferative activity against the NCI-60 human tumor cell line panel, with a mean GI50 of 0.98 μM, and shows strong cytotoxicity against leukemia, NSCLC, melanoma, ovarian, renal, and breast cancer cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 501.56
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Formula C26H23N5O4S
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SMILES
O=C(C(S1)=C(NC(C2=CC=C(OC)C=C2)=O)C3=C1C4=CC(NCC5=CNC=N5)=CC=C4N=C3)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NSC850143 Related Classifications
HY-183671 Related Classifications
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