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  3. Biochemical Assay Reagents
  4. NSC850143

NSC850143 is an antiproliferative agent. NSC850143 induces antiproliferative and cytotoxic effects in aggressive tumor cells. NSC850143 can be used in the research of cancers such as leukemia, non-small cell lung cancer, colon cancer, central nervous system cancer, melanoma, ovarian cancer, renal cancer, prostate cancer and breast cancer.

For research use only. We do not sell to patients.

NSC850143

NSC850143 Chemical Structure

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NSC850143 Related Antibodies

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Description

NSC850143 is an antiproliferative agent. NSC850143 induces antiproliferative and cytotoxic effects in aggressive tumor cells. NSC850143 can be used in the research of cancers such as leukemia, non-small cell lung cancer, colon cancer, central nervous system cancer, melanoma, ovarian cancer, renal cancer, prostate cancer and breast cancer[1].

In Vitro

NSC850143 (10 μM; 10-8-10-4 M) exhibits potent, broad antiproliferative activity against the NCI-60 human tumor cell line panel, with a mean GI50 of 0.98 μM, and shows strong cytotoxicity against leukemia, NSCLC, melanoma, ovarian, renal, and breast cancer cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

NSC850143 Related Antibodies
Molecular Weight

501.56

Formula

C26H23N5O4S
SMILES

O=C(C(S1)=C(NC(C2=CC=C(OC)C=C2)=O)C3=C1C4=CC(NCC5=CNC=N5)=CC=C4N=C3)OCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NSC850143 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC850143NSC 850143NSC-850143Biochemical Assay Reagentscolon cancerleukemiarenal cancerCNS cancerhuman tumor cellsPI3Kαovarian cancerhuman tumor modelsmelanomanon-small-cell lung cancerInhibitorinhibitorinhibit

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