A457
A457 is a prokineticin receptor PKR2 antagonist, with an IC50 of 102 nM. A457 can rescue the cell surface expression and function of P290S PKR2, but not W178S and G234D PKR2.
For research use only. We do not sell to patients.
- CAS No.: 1233923-95-9
- Formula: C26H33ClN2O3
- Molecular Weight:457.00
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
A457 (1 μM, 16 h) increases cell surface expression and rescued the function of P290S PKR2[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1233923-95-9
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Molecular Weight 457.00
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Formula C26H33ClN2O3
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SMILES
O=C(N(CC(C)C)CC1=CC(Cl)=C2OCCCOC2=C1)C3CN(CC3)CC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A457 Related Classifications
HY-129317 Related Classifications
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