Dalbinol
Dalbinol is a rotenoid compound. Dalbinol can inhibit Wnt/β-catenin signaling pathway and promote β-catenin degradation. Dalbinol inhibits tumor cells proliferation and induces apoptosis. Dalbinol has antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 41993-79-7
- Formula: C23H22O8
- Molecular Weight:426.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | ED50 |
<0.001 μg/mL
Compound: 6
|
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
|
[PMID: 8326318] |
| HCT-8 | ED50 |
<0.001 μg/mL
Compound: 6
|
Cytotoxicity against human HCT8 cells
Cytotoxicity against human HCT8 cells
|
[PMID: 8326318] |
| KB | ED50 |
<0.001 μg/mL
Compound: 6
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 8326318] |
| L5178Y | IC50 |
0.2 μM
Compound: 31
|
Cytotoxicity against mouse L5178Y cells by MTT assay
Cytotoxicity against mouse L5178Y cells by MTT assay
|
[PMID: 28075580] |
| LNCaP | ED50 |
5.4 μg/mL
Compound: 8
|
Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
|
[PMID: 17125241] |
| Lu1 | ED50 |
3.1 μg/mL
Compound: 8
|
Cytotoxicity against human Lu1 cells
Cytotoxicity against human Lu1 cells
|
[PMID: 17125241] |
| MCF7 | ED50 |
13.1 μg/mL
Compound: 8
|
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
|
[PMID: 17125241] |
| P388 | ED50 |
<0.001 μg/mL
Compound: 6
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 8326318] |
| RPMI-7951 | ED50 |
<0.001 μg/mL
Compound: 6
|
Cytotoxicity against human RPMI7951 cells
Cytotoxicity against human RPMI7951 cells
|
[PMID: 8326318] |
| TE-671 | ED50 |
<0.001 μg/mL
Compound: 6
|
Cytotoxicity against human TE671 cells
Cytotoxicity against human TE671 cells
|
[PMID: 8326318] |
Chemical Information
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CAS No. 41993-79-7
-
Molecular Weight 426.42
-
Formula C23H22O8
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SMILES
O[C@]12C3=CC(OC)=C(OC)C=C3OC[C@@]1([H])OC4=C(C[C@@H](O5)C(CO)=C)C5=CC=C4C2=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)