Targeted Organs/Cells

DSPE-PEG2000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells.

DSPE-PEG2000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). DSPE-PEG2000-CSTSMLKAC can be used for drug delivery DSPE-PEG2000-CSTSMLKAC enables targeted delivery of associated nanoliposomes to ischemic myocardial cells.

RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice.

DSPE-PEG3400-TAT is a PEG compound which composed of DSPE (HY-112530) and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3400-TAT can be used for drug delivery.

DSPE-PEG2000-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG2000-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG2000-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions.

DSPE-PEG5000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG5000-CSTSMLKAC can be used for drug delivery.

DMG-PEG2000-PTP (DMG-PEG2000-Mal-Cys-KTLLPTP) is a functionalized PEGylated phospholipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and a PTP (HY-P11850) peptide as a terminal targeting/functional ligand. DMG-PEG2000-PTP can be used in research on targeted drug delivery for pancreatic cancer.

DSG-PEG2000-GALA (DSG-PEG2000-Mal-Cys-WEAALAEALAEALAEHLAEALAEALEALAA) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a GALA (HY-P5423) peptide as a terminal targeting/functional ligand. DSG-PEG2000-GALA can be used for pH-responsive drug delivery, endosome escape and cytoplasmic drug release, and cytoplasmic delivery of nucleic acids (siRNA/mRNA).

DSG-PEG2000-KTP (DSG-PEG2000-Mal-Cys-KKEEEKKEEEKKEEEK) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and a KTP ((KKEEE)3K) (HY-P11452) peptide as a terminal targeting/functional ligand. DSG-PEG2000-KTP can be used in studies of renal targeted drug delivery.

DSG-PEG2000-CRPPR is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a CRPPR (HY-P10641A) peptide as a terminal targeting/functional ligand. DSG-PEG2000-CRPPR can be used in studies of cardiac-targeted drug delivery.

DSG-PEG2000-R8 (DSG-PEG2000-Mal-Cys-RRRRRRRR) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and an R8 peptide as a terminal targeting/functional ligand. DSG-PEG2000-R8 can be used in research on intracellular drug delivery, nucleic acid delivery, etc.

DSG-PEG2000-CSTSMLKAC is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and the CSTSMLKAC peptide as a terminal targeting/functional ligand. DSG-PEG2000-CSTSMLKAC can be used in research on targeted drug delivery for ischemic heart disease.

DMG-PEG2000-BR2 (DMG-PEG2000-Mal-Cys-RAGLQFPVGRLLRRLLR) is a functionalized PEGylated phospholipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and a BR2 peptide as a terminal targeting/functional ligand. DMG-PEG2000-BR2 can be used in research on targeted drug delivery for breast cancer.

DMG-PEG2000-APRPG (DMG-PEG2000-Mal-Cys-APRPG) is a functionalized PEGylated phospholipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and an APRPG peptide as a terminal targeting/functional ligand. DMG-PEG2000-APRPG can be used in research on tumor angiogenesis-targeted drug delivery.

DSG-PEG2000-TH (DSG-PEG2000-Mal-Cys-TH) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and a TH peptide as a terminal targeting/functional ligand. DSG-PEG2000-TH can be used in studies of tumor microenvironment-responsive drug delivery.

DMG-PEG2000-ESBP (DMG-PEG2000-Mal-Cys-DITWDQLWDLMK) is a functionalized PEGylated phospholipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and an ESBP peptide as a terminal targeting/functional ligand. DMG-PEG2000-ESBP can be used in research such as targeted drug delivery for inflammation.

DSG-PEG2000-YIGSR (DSG-PEG2000-Mal-Cys-YIGSR) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a YIGSR (HY-P0132) peptide as a terminal targeting/functional ligand. DSG-PEG2000-YIGSR can be used in research such as tumor-targeted drug delivery.

DSG-PEG2000-DHLASLWWGTEL (DSG-PEG2000-Mal-Cys-DHLASLWWGTEL) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and the DHLASLWWGTEL peptide as a terminal targeting/functional ligand. DSG-PEG2000-DHLASLWWGTEL can be used in research on targeted drug delivery for hepatocellular carcinoma.

DSG-PEG2000-VIP (DSG-PEG2000-Mal-Cys-HSDAVFTDNYTRLRKQMAVKKYLNSILN) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a VIP peptide as a terminal targeting/functional ligand. DSG-PEG2000-VIP can be used in research such as targeted drug delivery for breast cancer.

DSG-PEG2000-F3 (DSG-PEG2000-Mal-Cys-KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and an F3 (HY-P10997) peptide as a terminal targeting/functional ligand. DSG-PEG2000-F3 can be used in research such as tumor-targeted drug delivery.