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Cat. No.: HY-114814

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ORM-10921 free base

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ORM-10921 free base is a selective α-2C adrenergic receptor antagonist with a K_i of 1.4 nM. ORM-10921 free base displays potent antidepressant and antipsychotic-like effects.

For research use only. We do not sell to patients.

Purity: 98.08%
CAS No.: 610782-82-6
Formula: C₁₈H₂₃NO₂
Molecular Weight:285.38

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

ORM-10921 free base Chemical Structure

CAS No.: 610782-82-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ORM-10921 free base is a selective α-2C adrenergic receptor antagonist with a K_i of 1.4 nM. ORM-10921 free base displays potent antidepressant and antipsychotic-like effects^[1].

IC₅₀ & Target^[1]

Alpha-2C adrenergic receptor

1.4 nM (Ki)

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 610782-82-6
Appearance Solid
Molecular Weight 285.38
Formula C₁₈H₂₃NO₂
Color Light yellow to yellow
SMILES

C[C@@]1(CCCN2CCC3=C([C@]12[H])OC4=CC=CC=C43)COC
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jukka Sallinen, et al. Pharmacological characterisation of a structurally novel α2C-adrenoceptor antagonist ORM-10921 and its effects in neuropsychiatric models. Basic Clin Pharmacol Toxicol. 2013 Oct;113(4):239-49. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ORM-10921 free base

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ORM-10921 free base Related Classifications

HY-114814 Related Classifications