1. Oxprenolol

Oxprenolol (Ba 39089 free base) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.

For research use only. We do not sell to patients.

Oxprenolol Chemical Structure

Oxprenolol Chemical Structure

CAS No. : 6452-71-7

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Description

Oxprenolol (Ba 39089 free base) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].

In Vitro

Oxprenolol is lipophilic[3].
Oxprenolol shows permeability rate constant of 1.54 ± 1.54×10-3 cm/h across abdominal human skin[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Oxprenolol (200 mg/kg/day; p.o.; daily for 3 weeks) produces effective beta-blockade together with peak plasma drug levels within the normal clinical range[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male rats (230 to 300 g body wt) of the Wistar strain[2]
Dosage: 200 mg/kg
Administration: Administered orally; daily for 3 weeks
Result: This dosage produced effective beta-blockade.
Molecular Weight

265.35

Formula

C15H23NO3

CAS No.
SMILES

OC(COC1=CC=CC=C1OCC=C)CNC(C)C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Oxprenolol
Cat. No.:
HY-B1486A
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