P-gp-IN-33
P-gp-IN-33 (Compound 17a) is a P-gp inhibitor. P-gp-IN-33 binds the Verapamil (HY-14275)-binding pocket of P-gp. P-gp-IN-33 shows higher cytotoxicity against resistant non-small cell lung carcinoma cells than against non-resistant non-small cell lung carcinoma cells.
For research use only. We do not sell to patients.
- Formula: C40H46N6O8
- Molecular Weight:738.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 738.83
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Formula C40H46N6O8
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SMILES
C[C@@H]1CCC2[C@@]3(OO4)[C@H](O[C@@H](OC(CCC(NCCN5C=C(COC6=NC(C7=CC=CC=C7)=CC(C8=CC=CC=C8)=N6)N=N5)=O)=O)[C@@H]2C)O[C@@]4(C)CCC31
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)