1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
  3. PCSK9 modulator-3

PCSK9 modulator-3 (Compound 13) is a potent modulator of PCSK9 with an EC50 value of 2.46 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-3 has the potential for the research of hyperlipidemia.

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PCSK9 modulator-3 Chemical Structure

PCSK9 modulator-3 Chemical Structure

CAS No. : 2476490-18-1

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Description

PCSK9 modulator-3 (Compound 13) is a potent modulator of PCSK9 with an EC50 value of 2.46 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-3 has the potential for the research of hyperlipidemia[1].

Molecular Weight

297.26

Formula

C16H9F2N3O

CAS No.
SMILES

O=C(C1=NC2=CC=C(F)C=C2N1)C3=CNC4=C3C=CC=C4F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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PCSK9 modulator-3 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PCSK9 modulator-3
Cat. No.:
HY-146084
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