PD 4'-oxyacetic acid
Based on 1 Customer Validation
PD 4'-oxyacetic acid is a carboxylic acid-functionalized cereblon ligand that can be used for PROTAC Degrader development.
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- Purity: 99.69%
- CAS No.: 2633633-12-0
- 화학식: C12H12N2O5
- 분자량:264.24
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2633633-12-0
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Appearance Solid
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분자량 264.24
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화학식 C12H12N2O5
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Color White to off-white
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SMILES
O=C(O)COC1=CC=C(N(C(N2)=O)CCC2=O)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 12.5 mg/mL (47.31 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7845 mL | 18.9224 mL | 37.8448 mL | 94.6120 mL |
| 5 mM | 0.7569 mL | 3.7845 mL | 7.5690 mL | 18.9224 mL | |
| 10 mM | 0.3784 mL | 1.8922 mL | 3.7845 mL | 9.4612 mL | |
| 15 mM | 0.2523 mL | 1.2615 mL | 2.5230 mL | 6.3075 mL | |
| 20 mM | 0.1892 mL | 0.9461 mL | 1.8922 mL | 4.7306 mL | |
| 25 mM | 0.1514 mL | 0.7569 mL | 1.5138 mL | 3.7845 mL | |
| 30 mM | 0.1261 mL | 0.6307 mL | 1.2615 mL | 3.1537 mL | |
| 40 mM | 0.0946 mL | 0.4731 mL | 0.9461 mL | 2.3653 mL |