PD07
PD07 is an orally active AChE inhibitor (IC50: 0.29 μM for hAChE). PD07 also inhibits ChEs, BACE1 (IC50: 13.42 μM), and Aβ1–42 aggregation in in vitro. PD07 is an antioxidant, and shows DPPH inhibitory activity (IC50: 26.46 μM). PD07 improves memory and cognition in Scopolamine (HY-N0296)-induced amnesia rats. PD07 can be used for research of Alzheimer’s disease.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C23H21ClN2O4
- Molecular Weight:424.88
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
0.29 μM (hAChE)[1]
Chemical Information
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Molecular Weight 424.88
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Formel C23H21ClN2O4
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SMILES
ClC1=CC=C(C(N2CCN(C(/C=C/C=C/C3=CC(OCO4)=C4C=C3)=O)CC2)=O)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)