PDE4-IN-13
PDE4-IN-13 is a PDE4 inhibitor with an IC50 of 1.56 μM. PDE4-IN-13 shows anti-inflammatory and antioxidant properties, and can be used for chronic obstructive pulmonary disease (COPD) research.
For research use only. We do not sell to patients.
- Formula: C20H20O5
- Molecular Weight:340.37
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
PDE4 1.56 μM (IC50) |
PDE4-IN-13 (compound 6o) reducesTNF-α production induced by lipopolysaccharide (LPS) in RAW264.7 macrophages and malondialdehyde (MDA) production induced by Fe2+ in mouse lung homogenate. Meanwhile, PDE4-IN-13 shows outstanding abilities in reducing Fe3+ and complexing Fe2+[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 340.37
-
Formula C20H20O5
-
SMILES
O=C(C1=CC=C(O)C(O)=C1)/C=C/C2=CC=C(OC)C(OCC3CC3)=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)