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Cat. No.: HY-107778R

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PF-9366 (Standard)

PF-9366 (Standard) is the analytical standard of PF-9366 (HY-107778). This product is intended for research and analytical applications. PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor, with an IC₅₀ of 420 nM and a K_d of 170 nM.

For research use only. We do not sell to patients.

CAS No.: 72882-78-1
Formula: C₂₀H₁₉ClN₄
Molecular Weight:350.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PF-9366 (Standard) Chemical Structure

CAS No.: 72882-78-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

IC50: 420 nM (Mat2A)^[1]
Kd: 170 nM (Mat2A)^[1]

Chemical Information

CAS No. 72882-78-1
Molecular Weight 350.84
Formula C₂₀H₁₉ClN₄
SMILES

CN(C)CCC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=CC=CC=C4)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Quinlan CL, et al. Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A. Nat Chem Biol. 2017 Jul;13(7):785-792. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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