2. PI3K/Akt/mTOR
  3. PI3K mTOR
  4. PI3K/mTOR Inhibitor-17

PI3K/mTOR Inhibitor-17 (compound 5nh) is a potent inhibitor of PI3K/mTOR, with the inhibitor of 0.45 and 2.9 nM for PI3Kα and mTOR, respectively. PI3K/mTOR Inhibitor-17 plays an important role in cancer research.

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PI3K/mTOR Inhibitor-17

PI3K/mTOR Inhibitor-17 Estructura química

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PI3K/mTOR Inhibitor-17 Related Antibodies

Top Publications Citing Use of Products

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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mTOR mTORC1 mTORC2

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Descripciòn

PI3K/mTOR Inhibitor-17 (compound 5nh) is a potent inhibitor of PI3K/mTOR, with the inhibitor of 0.45 and 2.9 nM for PI3Kα and mTOR, respectively. PI3K/mTOR Inhibitor-17 plays an important role in cancer research[1].

IC50 & Target

PI3Kα

0.45 nM (IC50)

Peso molecular

588.66

Fòrmula

C30H36N8O5
SMILES

O=C(NC1=CC=C(C(N2[C@H](CO)CCC2)=O)C=C1)NC3=CC=C(C4=NC(N5CCOCC5)=NC(N6CCOCC6)=N4)C=C3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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PI3K/mTOR Inhibitor-17 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3K/mTOR Inhibitor-17PI3KmTORPhosphoinositide 3-kinaseMammalian target of Rapamycinnon-small-cell lung cancer (NSCLC) cell linesInhibitorinhibitorinhibit

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Nombre del producto:
PI3K/mTOR Inhibitor-17
Cat. No.:
HY-170656
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