PIM-IN-6
PIM-IN-6 is an inhibitor of PIM1 and PIM2, with an IC50 of 254 nM against PIM1 and an IC50 of 1.78 μM against PIM2. PIM-IN-6 can be used for the research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 2698319-19-4
- Formula: C15H18ClFN4O
- Molecular Weight:324.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PIM1 254 nM (IC50) |
PIM2 1.78 μM (IC50) |
PIM-IN-6 inhibits purified PIM1 and PIM2 kinases with IC50 values of 254 nM and 1780 nM, respectively[1].
PIM-IN-6 reduces KG1 human acute myeloid leukemia cell viability with an EC50 of 7230 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2698319-19-4
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Molecular Weight 324.78
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Formula C15H18ClFN4O
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SMILES
C[C@H]([C@]1(CCNC1)F)N2C3=NC(C(N)=O)=CC(Cl)=C3C(C)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PIM-IN-6 Related Classifications
HY-184811 Related Classifications
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