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United States

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Art. -Nr.: HY-184933

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PIN1-IN-8

PIN1-IN-8 (Compound T41) is a covalent inhibitor of Pin1, with IC₅₀ values of 0.13 μM and 0.02 μM against purified Pin1 and Pin1 enzymatic activity, respectively. PIN1-IN-8 can be used in triple-negative breast cancer research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₁₅H₁₇NO₅S
Molecular Weight:323.36

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

PIN1-IN-8 Chemical Structure

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Menge

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

Chemical Information

Molecular Weight 323.36
Formel C₁₅H₁₇NO₅S
SMILES

O=C(NC1CS(CC1)(=O)=O)/C=C\C(OCC2=CC=CC=C2)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Tian M, et al. Structure-Based Discovery of (E)- and (Z)-4-Oxobut-2-enoate Derivatives as Novel Covalent Pin1 Inhibitors with Antitumor Activity. J Med Chem. 2026 Jul 2.
[Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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