Platyphyllonol
Platyphyllonol (Platyphyllone) can be isolated from A. japonica. Platyphyllonol shows cytotoxic effects on MCF-7 cells with IC50 values of 46.9 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 41137-85-3
- Formula: C19H22O4
- Molecular Weight:314.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16-4A5 | IC50 |
>10 μM
Compound: 14
|
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
|
[PMID: 23910596] |
| HSC-T6 | IC50 |
54.9 μM
Compound: 3
|
Antifibrotic activity against rat HSC-T6 cells assessed as inhibition of proliferation after 48 hrs by BrdU incorporation assay
Antifibrotic activity against rat HSC-T6 cells assessed as inhibition of proliferation after 48 hrs by BrdU incorporation assay
|
[PMID: 21504848] |
| RAW264.7 | IC50 |
30 μM
Compound: 28
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
|
[PMID: 33422907] |
| RAW264.7 | IC50 |
46.37 μM
Compound: 15
|
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess reaction based spectrophotometry
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess reaction based spectrophotometry
|
[PMID: 21807513] |
Chemical Information
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CAS No. 41137-85-3
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Molecular Weight 314.38
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Formula C19H22O4
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SMILES
OC(C=C1)=CC=C1CCC(C[C@@H](O)CCC2=CC=C(O)C=C2)=O
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Synonyms
Platyphyllone
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)