Pomalidomide-C3-NHS ester
Based on 1 Customer Validation
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker.
For research use only. We do not sell to patients.
- Purity: 98.70%
- CAS No.: 2828476-87-3
- Formula: C21H20N4O8
- Molecular Weight:456.41
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2828476-87-3
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Appearance Solid
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Molecular Weight 456.41
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Formula C21H20N4O8
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Color Light yellow to yellow
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SMILES
O=C(C1=C2C=CC=C1NCCCC(ON3C(CCC3=O)=O)=O)N(C4C(NC(CC4)=O)=O)C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (219.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (243 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1910 mL | 10.9551 mL | 21.9101 mL | 54.7753 mL |
| 5 mM | 0.4382 mL | 2.1910 mL | 4.3820 mL | 10.9551 mL | |
| 10 mM | 0.2191 mL | 1.0955 mL | 2.1910 mL | 5.4775 mL | |
| 15 mM | 0.1461 mL | 0.7303 mL | 1.4607 mL | 3.6517 mL | |
| 20 mM | 0.1096 mL | 0.5478 mL | 1.0955 mL | 2.7388 mL | |
| 25 mM | 0.0876 mL | 0.4382 mL | 0.8764 mL | 2.1910 mL | |
| 30 mM | 0.0730 mL | 0.3652 mL | 0.7303 mL | 1.8258 mL | |
| 40 mM | 0.0548 mL | 0.2739 mL | 0.5478 mL | 1.3694 mL | |
| 50 mM | 0.0438 mL | 0.2191 mL | 0.4382 mL | 1.0955 mL | |
| 60 mM | 0.0365 mL | 0.1826 mL | 0.3652 mL | 0.9129 mL | |
| 80 mM | 0.0274 mL | 0.1369 mL | 0.2739 mL | 0.6847 mL | |
| 100 mM | 0.0219 mL | 0.1096 mL | 0.2191 mL | 0.5478 mL |
Pomalidomide-C3-NHS ester Related Classifications
HY-148142 Related Classifications
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