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Cat. No.: HY-146667

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POP-IN-1

POP-IN-1 (Compound 12h) is a potent inhibitor of POP with an K_i of 0.009 μM. POP-IN-1 has the potential for the research of neurodegenerative diseases and cancer progression.

For research use only. We do not sell to patients.

CAS No.: 2743432-99-5
Formula: C₂₂H₃₀BNO₃S
Molecular Weight:399.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

POP-IN-1 Chemical Structure

CAS No.: 2743432-99-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

POP-IN-1 (Compound 12h) is a potent inhibitor of POP with an K_i of 0.009 μM. POP-IN-1 has the potential for the research of neurodegenerative diseases and cancer progression^[1].

Chemical Information

CAS No. 2743432-99-5
Molecular Weight 399.35
Formula C₂₂H₃₀BNO₃S
SMILES

[H][C@@]12C[C@@H]3C[C@H]([C@@]1(OB(O2)C4CCCN4C(C5=C(C=CC=C5)SC)=O)C)C3(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Plescia J, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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