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United States

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Cat. No.: HY-146667

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POP-IN-1

POP-IN-1 (Compound 12h) is a potent inhibitor of POP with an K_i of 0.009 μM. POP-IN-1 has the potential for the research of neurodegenerative diseases and cancer progression.

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CAS No.: 2743432-99-5
Formule: C₂₂H₃₀BNO₃S
Masse moléculaire:399.35

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

POP-IN-1 Chemical Structure

CAS No.: 2743432-99-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

POP-IN-1 (Compound 12h) is a potent inhibitor of POP with an K_i of 0.009 μM. POP-IN-1 has the potential for the research of neurodegenerative diseases and cancer progression^[1].

Chemical Information

CAS No. 2743432-99-5
Masse moléculaire 399.35
Formule C₂₂H₃₀BNO₃S
SMILES

[H][C@@]12C[C@@H]3C[C@H]([C@@]1(OB(O2)C4CCCN4C(C5=C(C=CC=C5)SC)=O)C)C3(C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Plescia J, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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