PPARδ agonist 3
PPARδ agonist 3 is a selective PPARδ agonist that induces PPARδ-mediated transactivation with an EC50 of 25.0 nM. PPARδ agonist 3 can be used in research related to metabolic diseases and inflammation.
For research use only. We do not sell to patients.
- CAS No.: 851528-80-8
- Formula: C21H23F3O5S
- Molecular Weight:444.47
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
PPARδ 25.0 nM (EC50) |
In Vitro
PPARδ agonist 3 (3Sb) is a potent human PPARδ agonist in a cell-based transactivation assay with an EC50 of 25.0 nM and 93% efficacy, while showing EC50 >1 μM against PPARα and PPARγ[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 851528-80-8
-
Molecular Weight 444.47
-
Formula C21H23F3O5S
-
SMILES
O(CC(O)=O)C1=C(C)C=C(SC[C@H](COC2=CC=C(C(F)(F)F)C=C2)OCC)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)