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Cat. No.: HY-140044

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Propargyl-PEG2-methylamine

(Synonyms: Propargyl-PEG2-NHMe)

Propargyl-PEG2-methylamine (Propargyl-PEG2-NHMe) is a PEG derivative containing a propargyl group and methylamine group. Propargyl-PEG2-methylamine is an PROTAC linker used in the synthesis of PROTACs. Propargyl-PEG2-methylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

CAS No.: 1835759-76-6
Formula: C₈H₁₅NO₂
Molecular Weight:157.21

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Propargyl-PEG2-methylamine Chemical Structure

CAS No.: 1835759-76-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All PROTAC Linkers Isoforms :

Chemical Information

CAS No. 1835759-76-6
Molecular Weight 157.21
Formula C₈H₁₅NO₂
SMILES

C#CCOCCOCCNC
Synonyms

Propargyl-PEG2-NHMe
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Propargyl-PEG2-methylamine

All PROTAC Linkers Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Propargyl-PEG2-methylamine Related Classifications

HY-140044 Related Classifications