Propargyl-PEG5-OH
Based on 1 Customer Validation
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 1036204-60-0
- Formula: C13H24O6
- Molecular Weight:276.33
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1036204-60-0
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Appearance Liquid (Density: 1.078 g/cm3)
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Molecular Weight 276.33
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Formula C13H24O6
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Color Colorless to light yellow
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SMILES
OCCOCCOCCOCCOCCOCC#C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (361.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6189 mL | 18.0943 mL | 36.1886 mL | 90.4715 mL |
| 5 mM | 0.7238 mL | 3.6189 mL | 7.2377 mL | 18.0943 mL | |
| 10 mM | 0.3619 mL | 1.8094 mL | 3.6189 mL | 9.0472 mL | |
| 15 mM | 0.2413 mL | 1.2063 mL | 2.4126 mL | 6.0314 mL | |
| 20 mM | 0.1809 mL | 0.9047 mL | 1.8094 mL | 4.5236 mL | |
| 25 mM | 0.1448 mL | 0.7238 mL | 1.4475 mL | 3.6189 mL | |
| 30 mM | 0.1206 mL | 0.6031 mL | 1.2063 mL | 3.0157 mL | |
| 40 mM | 0.0905 mL | 0.4524 mL | 0.9047 mL | 2.2618 mL | |
| 50 mM | 0.0724 mL | 0.3619 mL | 0.7238 mL | 1.8094 mL | |
| 60 mM | 0.0603 mL | 0.3016 mL | 0.6031 mL | 1.5079 mL | |
| 80 mM | 0.0452 mL | 0.2262 mL | 0.4524 mL | 1.1309 mL | |
| 100 mM | 0.0362 mL | 0.1809 mL | 0.3619 mL | 0.9047 mL |
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