Propargyl-PEG6-NH2
Based on 1 Customer Validation
Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 1198080-04-4
- Formula: C15H29NO6
- Molecular Weight:319.39
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1198080-04-4
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Appearance Liquid (Density: 1.058±0.06 g/cm3)
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Molecular Weight 319.39
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Formula C15H29NO6
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Color Colorless to light yellow
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SMILES
C#CCOCCOCCOCCOCCOCCOCCN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (782.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1310 mL | 15.6548 mL | 31.3097 mL | 78.2742 mL |
| 5 mM | 0.6262 mL | 3.1310 mL | 6.2619 mL | 15.6548 mL | |
| 10 mM | 0.3131 mL | 1.5655 mL | 3.1310 mL | 7.8274 mL | |
| 15 mM | 0.2087 mL | 1.0437 mL | 2.0873 mL | 5.2183 mL | |
| 20 mM | 0.1565 mL | 0.7827 mL | 1.5655 mL | 3.9137 mL | |
| 25 mM | 0.1252 mL | 0.6262 mL | 1.2524 mL | 3.1310 mL | |
| 30 mM | 0.1044 mL | 0.5218 mL | 1.0437 mL | 2.6091 mL | |
| 40 mM | 0.0783 mL | 0.3914 mL | 0.7827 mL | 1.9569 mL | |
| 50 mM | 0.0626 mL | 0.3131 mL | 0.6262 mL | 1.5655 mL | |
| 60 mM | 0.0522 mL | 0.2609 mL | 0.5218 mL | 1.3046 mL | |
| 80 mM | 0.0391 mL | 0.1957 mL | 0.3914 mL | 0.9784 mL | |
| 100 mM | 0.0313 mL | 0.1565 mL | 0.3131 mL | 0.7827 mL |
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