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United States

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製品番号: HY-186312

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PROTAC IRF5 degrader-2

PROTAC IRF5 degrader-2 (I-7) is a bifunctional IRF5 PROTAC degrader. PROTAC IRF5 degrader-2 recruits IRF5 to the E3 ubiquitin ligase for targeted degradation. PROTAC IRF5 degrader-2 is applicable to the research of autoimmune diseases.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₄₇H₅₁F₄N₉O₄
分子量:881.96

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

PROTAC IRF5 degrader-2 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target

^[1]

IRF5

PROTACs アイソフォーム固有の製品をすべて表示 :

体外実験

IRF5 is a transcription factor of the IRF family, which mainly mediates innate immune responses downstream of pattern recognition receptors such as TLR, drives the production of pro-inflammatory cytokines and type I interferons, and regulates the polarization of macrophages toward the M1 pro-inflammatory phenotype. Its abnormal activation is closely associated with autoimmune diseases such as lupus erythematosus.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

分子量 881.96
分子式 C₄₇H₅₁F₄N₉O₄
SMILES

FC1(CCC(CN2C=NC(C3=NC(OC4=CC=CC5=C4NC(N5C)=O)=CC(C6CCC(N7CCC(C8=CC=C9C(N(C)N=C9C%10CCC(NC%10=O)=O)=C8)C(C7)(F)F)CC6)=C3)=C2)CC1)F
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (282 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. ZHANG, Yi, et al. IRF5 DEGRADERS AND USES THEREOF. WO2026156070A1. 2026.07.23.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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