PROTAC IRF5 degrader-2
PROTAC IRF5 degrader-2 (I-7) is a bifunctional IRF5 PROTAC degrader. PROTAC IRF5 degrader-2 recruits IRF5 to the E3 ubiquitin ligase for targeted degradation. PROTAC IRF5 degrader-2 is applicable to the research of autoimmune diseases.
For research use only. We do not sell to patients.
- Formula: C47H51F4N9O4
- Molecular Weight:881.96
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All PROTACs Isoforms
More
Biological Activity
Description
IC50 & Target
[1]|
IRF5 |
In Vitro
IRF5 is a transcription factor of the IRF family, which mainly mediates innate immune responses downstream of pattern recognition receptors such as TLR, drives the production of pro-inflammatory cytokines and type I interferons, and regulates the polarization of macrophages toward the M1 pro-inflammatory phenotype. Its abnormal activation is closely associated with autoimmune diseases such as lupus erythematosus.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 881.96
-
Formula C47H51F4N9O4
-
SMILES
FC1(CCC(CN2C=NC(C3=NC(OC4=CC=CC5=C4NC(N5C)=O)=CC(C6CCC(N7CCC(C8=CC=C9C(N(C)N=C9C%10CCC(NC%10=O)=O)=C8)C(C7)(F)F)CC6)=C3)=C2)CC1)F
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC IRF5 degrader-2 Related Classifications
HY-186312 Related Classifications
Powered by Bioz