Proteasome-IN-7
Proteasome-IN-7 (Compound 6f) is an epoxyketone macrocyclic peptidyl proteasome inhibitor (IC50 value of 37.92 nM for 20S proteasome ChT-L subunit). Proteasome-IN-7 displays robust antiproliferative effects against multiple myeloma, acute lymphoblastic leukemia and non-small cell lung cancer.
For research use only. We do not sell to patients.
- Formula: C48H56N6O10S
- Molecular Weight:909.06
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50 value of 37.92 nM for 20S proteasome ChT-L subunit
Chemical Information
-
Molecular Weight 909.06
-
Formula C48H56N6O10S
-
SMILES
COC(/C=C(C1=C2C=CC=CC2=C3SC[C@H](NC([C@@H](NC([C@H](CCCCN31)NC(C4=CC=CN=C4)=O)=O)CCC5=CC=CC=C5)=O)C(N[C@H](C([C@]6(CO6)C)=O)CC(C)C)=O)\C(OC)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)