CaMKK1
CaMKK1 (CaMKKα) is one of two calcium/calmodulin-dependent protein kinase kinases in mammals. Triggered by Ca2+/calmodulin, it phosphorylates and activates CaMKI and CaMKIV but not CaMKII, which distinguishes it from the broader substrate range of CaMKK2. CaMKK1 functions predominantly in the nucleus and has been implicated in CaMKIV-dependent activation of transcription factors such as CREB, supporting neuronal gene regulation, T-cell development and spermatogenesis-related signaling. Its expression is more restricted than that of CaMKK2, with particularly high levels in testis. Recombinant CaMKK1 serves as an upstream activator in CaMK cascade assays and in studies of calcium-dependent transcriptional control.
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CaMKK1 Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
