FGF-20
FGF-20 is a brain-enriched ligand with a well-defined neuroprotective role. It is expressed in the substantia nigra, where it promotes the survival and neurite outgrowth of dopaminergic neurons through FGFR1c, and it is also found in cerebellum and cortex. Genetic association studies have repeatedly linked variants in the FGF20 region, including a polymorphism in an miR-433 binding site, to Parkinson's disease risk. FGF-20 additionally supports hair-follicle and inner-ear cell survival. Recombinant FGF-20 is used in dopaminergic neuron cultures and Parkinson's disease models, neuroprotection assays and studies of FGF signaling in the central nervous system.
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FGF-20 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
