PIP4K2B
PIP4K2B (PI5P4Kβ) is a ubiquitously expressed type 2 PI5P 4-kinase that consumes phosphatidylinositol-5-phosphate to form PI(4,5)P2, positioning it as a key controller of PI5P-dependent signaling. It distributes across nuclear and cytoplasmic compartments and associates with endosomal membranes, where it influences trafficking and growth-factor signaling. PIP4K2B has been linked to regulation of cell proliferation, to AKT and mTOR pathway output, and to the DNA-damage response; its expression is elevated in several tumor types, and small-molecule inhibitors of the PIP4K2 family are being explored for cancer and for disorders of mTOR signaling.
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PIP4K2B Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
