Mosquitocidal activities of octacosane from Moschosma polystachyum Linn (lamiaceae)

  • J Ethnopharmacol. 2004 Jan;90(1):87-9. doi: 10.1016/j.jep.2003.09.030.
S Rajkumar  1 ,  A Jebanesan
Affiliations
  • 1. Department of Zoology, Annamalai University, Annamalainagar 608 002, Tamil Nadu, India.
PMID: 14698514 DOI: 10.1016/j.jep.2003.09.030
Abstract

The toxicity of the plant Moschosma polystachyum was evaluated against mosquito Culex quinquefasciatus. The crude leaf extract and active compound octacosane showed negligible mortality against early third instar larvae of Culex quinquefasciatus. The 24 h LC(50) value was observed at 153.2+/-1.3 mg/l and 7.2+/-1.7 mg/l for crude leaf extract and active compound octacosane, respectively. The repellent activity of active compound octacosane at 1.0 and 2.5 mg/cm(2) concentration gave 85.2+/-1.7 min and 54.6+/-2.3 min protection, respectively. The total percentage protection of octacosane was 96.2+/-0.9 at 2.5 mg/cm(2) and 86.4+/-1.3 at 1.0 mg/cm(2) concentration.

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