Novel triterpenoid saponins from the seeds of Celosia argentea L

  • Nat Prod Res. 2013 Aug;27(15):1353-60. doi: 10.1080/14786419.2012.740034.
Qing Bin Wu  1 ,  Yan Wang ,  Lin Liang ,  Qian Jiang ,  Mei Li Guo ,  Jun Jie Zhang
Affiliations
  • 1. Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, P.R. China.
PMID: 23157342 DOI: 10.1080/14786419.2012.740034
Abstract

Two new triterpenoid saponins celosin I (1) and celosin II (2) were isolated from the seeds of Celosia argentea L. (Amaranthaceae). The structures of the two new compounds were elucidated based on chemical analysis and spectral methods (IR, 1-D and 2-D NMR, ESI-MS, HR-ESI-MS). They exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice.

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