Caged polyprenylated xanthones from the resin of Garcinia hanburyi

  • Fitoterapia. 2016 Mar:109:106-12. doi: 10.1016/j.fitote.2015.12.002.
Yu Chen  1 ,  Shiwen He  2 ,  Chu Tang  2 ,  Jun Li  2 ,  Guangzhong Yang  3
Affiliations
  • 1. College of Chemistry and Material Sciences, South Central University for Nationalities, 182 Minyuan Road, Wuhan 430074, PR China.
  • 2. College of Pharmacy, South Central University for Nationalities, 182 Minyuan Road, Wuhan 430074, PR China.
  • 3. College of Pharmacy, South Central University for Nationalities, 182 Minyuan Road, Wuhan 430074, PR China. Electronic address: [email protected].
PMID: 26688377 DOI: 10.1016/j.fitote.2015.12.002
Abstract

Five new caged polyprenylated Xanthones (1a, 2a, 3, 10a and 10b), and 12 known related compounds were isolated from the resin of Garcinia hanburyi. Their structures were elucidated by detailed spectroscopic analyses and their α-glucosidase inhibitory activities were investigated in vitro. Most of Xanthones showed modest inhibitory activity against α-glucosidase.

Keywords
Garcinia hanburyi; Polyprenylated xanthones; α-Glucosidase inhibitory activity.
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