Genetic tracing uncovers the importance of epithelial-to-mesenchymal transition in small cell lung cancer chemotherapy resistance but not metastasis

  • Cell Discov. 2024 Jun 4;10(1):60. doi: 10.1038/s41421-024-00687-8.
Yuting Chen  #  1  2 ,  Chenchen Guo  #  2 ,  Xinlei Cai  3  4 ,  Liang Hu  2 ,  Xinyuan Tong  2 ,  Yun Xue  2  3 ,  Qiqi Zhao  2  3 ,  Tengfei Zhang  2  4 ,  Yuan Chen  2  4 ,  Yongting Fang  2  4 ,  Yayi He  5 ,  Yan Li  6  7 ,  Bin Zhou  8  9  10  11 ,  Hongbin Ji  12  13  14  15
Affiliations
  • 1. School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • 2. Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
  • 3. School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
  • 4. University of Chinese Academy of Sciences, Beijing, China.
  • 5. Department of Medical Oncology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
  • 6. Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai, Shandong, China.
  • 7. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • 8. School of Life Science and Technology, ShanghaiTech University, Shanghai, China. [email protected].
  • 9. Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China. [email protected].
  • 10. School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. [email protected].
  • 11. University of Chinese Academy of Sciences, Beijing, China. [email protected].
  • 12. School of Life Science and Technology, ShanghaiTech University, Shanghai, China. [email protected].
  • 13. Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China. [email protected].
  • 14. School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. [email protected].
  • 15. University of Chinese Academy of Sciences, Beijing, China. [email protected].
  • # Contributed equally.
PMID: 38834595 DOI: 10.1038/s41421-024-00687-8
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