Py-MPB-amino-C3-PBD
Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity.
For research use only. We do not sell to patients.
- CAS No.: 2412924-07-1
- Formula: C41H44N8O6
- Molecular Weight:744.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Pyrrolobenzodiazepines |
Py-MPB-amino-C3-PBD (compound 73) shows cytotoxicity with IC50s of 301, 144.1 and 37.5 nM for U138-MG, A431, and REH cells, respectively. Py-MPB-amino-C3-PBD possesses potent anti-bacterial effects against the gram negative strain E. coli K12, with potency of 2 pg/mL determined[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2412924-07-1
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Molecular Weight 744.84
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Formula C41H44N8O6
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SMILES
O=C(N(CCCC1)[C@]1([H])CN2)C3=C2C=C(OCCCC(NC4=CN(C)C(C(NC5=CC=C(C6=CN(C)C(C(NC7=CC=NC=C7)=O)=C6)C=C5)=O)=C4)=O)C(OC)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Py-MPB-amino-C3-PBD Related Classifications
HY-135901 Related Classifications
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