1. Antibody-drug Conjugate/ADC Related
    Anti-infection
  2. ADC Cytotoxin
    Bacterial
  3. Py-MPB-amino-C3-PBD

Py-MPB-amino-C3-PBD 

Cat. No.: HY-135901
Handling Instructions

Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity.

For research use only. We do not sell to patients.

Py-MPB-amino-C3-PBD Chemical Structure

Py-MPB-amino-C3-PBD Chemical Structure

CAS No. : 2412924-07-1

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Description

Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1].

IC50 & Target[1] [1] [1]

Pyrrolobenzodiazepines

 

In Vitro

Py-MPB-amino-C3-PBD (compound 73) shows cytotoxicity with IC50s of 301, 144.1 and 37.5 nM for U138-MG, A431, and REH cells, respectively. Py-MPB-amino-C3-PBD possesses potent anti-bacterial effects against the gram negative strain E. coli K12, with potency of 2 pg/mL determined[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

744.84

Formula

C41H44N8O6

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
Py-MPB-amino-C3-PBD
Cat. No.:
HY-135901
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