(R)-TTA-P2
Based on 1 Customer Validation
(R)-TTA-P2 is the isomer of TTA-P2 (HY-10035), and can be used as an experimental control. TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease.
For research use only. We do not sell to patients.
- Purity: 99.95%
- Formula: C21H29Cl2FN2O2
- Molecular Weight:431.37
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Calcium Channel Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 431.37
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Formula C21H29Cl2FN2O2
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Color Off-white to light yellow
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SMILES
CC(C)(OCC1)C[C@@H]1CN2CCC(F)(CC2)CNC(C3=CC(Cl)=CC(Cl)=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (115.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3182 mL | 11.5910 mL | 23.1820 mL | 57.9549 mL |
| 5 mM | 0.4636 mL | 2.3182 mL | 4.6364 mL | 11.5910 mL | |
| 10 mM | 0.2318 mL | 1.1591 mL | 2.3182 mL | 5.7955 mL | |
| 15 mM | 0.1545 mL | 0.7727 mL | 1.5455 mL | 3.8637 mL | |
| 20 mM | 0.1159 mL | 0.5795 mL | 1.1591 mL | 2.8977 mL | |
| 25 mM | 0.0927 mL | 0.4636 mL | 0.9273 mL | 2.3182 mL | |
| 30 mM | 0.0773 mL | 0.3864 mL | 0.7727 mL | 1.9318 mL | |
| 40 mM | 0.0580 mL | 0.2898 mL | 0.5795 mL | 1.4489 mL | |
| 50 mM | 0.0464 mL | 0.2318 mL | 0.4636 mL | 1.1591 mL | |
| 60 mM | 0.0386 mL | 0.1932 mL | 0.3864 mL | 0.9659 mL | |
| 80 mM | 0.0290 mL | 0.1449 mL | 0.2898 mL | 0.7244 mL | |
| 100 mM | 0.0232 mL | 0.1159 mL | 0.2318 mL | 0.5795 mL |