1. Cell Cycle/DNA Damage
  2. RAD51
  3. RAD51-IN-3

RAD51-IN-3 is a Rad51 inhibitor extracted from patent WO2019051465A1, compound Example 66A.

For research use only. We do not sell to patients.

RAD51-IN-3 Chemical Structure

RAD51-IN-3 Chemical Structure

CAS No. : 2301084-99-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 1077 In-stock
Solution
10 mM * 1 mL in DMSO USD 1077 In-stock
Solid
5 mg USD 780 In-stock
10 mg USD 1250 In-stock
25 mg USD 2580 In-stock
50 mg USD 4000 In-stock
100 mg USD 6400 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

RAD51-IN-3 is a Rad51 inhibitor extracted from patent WO2019051465A1, compound Example 66A[1].

IC50 & Target

Rad51[1]

Molecular Weight

627.82

Formula

C31H41N5O5S2

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=[S](NC(C)(C)C)(C1=C(C2=CN=C([C@](CC3)([H])CC[C@H]3NC(OC(C)C)=O)S2)C=CC(NC(NCC4=CC=CC=C4)=O)=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (159.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5928 mL 7.9641 mL 15.9281 mL
5 mM 0.3186 mL 1.5928 mL 3.1856 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5928 mL 7.9641 mL 15.9281 mL 39.8203 mL
5 mM 0.3186 mL 1.5928 mL 3.1856 mL 7.9641 mL
10 mM 0.1593 mL 0.7964 mL 1.5928 mL 3.9820 mL
15 mM 0.1062 mL 0.5309 mL 1.0619 mL 2.6547 mL
20 mM 0.0796 mL 0.3982 mL 0.7964 mL 1.9910 mL
25 mM 0.0637 mL 0.3186 mL 0.6371 mL 1.5928 mL
30 mM 0.0531 mL 0.2655 mL 0.5309 mL 1.3273 mL
40 mM 0.0398 mL 0.1991 mL 0.3982 mL 0.9955 mL
50 mM 0.0319 mL 0.1593 mL 0.3186 mL 0.7964 mL
60 mM 0.0265 mL 0.1327 mL 0.2655 mL 0.6637 mL
80 mM 0.0199 mL 0.0996 mL 0.1991 mL 0.4978 mL
100 mM 0.0159 mL 0.0796 mL 0.1593 mL 0.3982 mL
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RAD51-IN-3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
RAD51-IN-3
Cat. No.:
HY-136604
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