Rexaceract
Based on 1 Customer Validation
Rexaceract (Rexaceractum) is a heteroaryl compound that binds to β-glucocerebrosidase. Rexaceract maintains the conformational stability of β-glucocerebrosidase and exhibits activating activity. Rexaceract can be used in the research of nervous system-related diseases such as neurodegenerative diseases with Parkinsonism, epilepsy, and schizophrenia.
For research use only. We do not sell to patients.
- CAS No.: 2648407-86-5
- Formula: C21H19FN4O
- Molecular Weight:362.40
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Rexaceract (Example 71) (6-50 μM; 4-day incubation) binds allosterically to β-glucocerebrosidase in human fibroblasts carrying the L444P mutation, increasing the enzyme activity by 1.2- to 1.7-fold[1].\n
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 2648407-86-5
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Appearance Solid
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Molecular Weight 362.40
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Formula C21H19FN4O
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SMILES
O=C(C1=NC(NC2=C(F)C=CC=C2)=CC(N)=C1)NC3CC4=C(C3)C=CC=C4
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Synonyms
Rexaceractum
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rexaceract Related Classifications
HY-184093 Related Classifications
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