RIPK1-IN-29
RIPK1-IN-29 (Compound 22) is a RIPK1 inhibitor, with an IC50 of 6.9 nM. RIPK1-IN-29 exerts anti-necroptotic (Apoptosis) activity by inhibiting RIPK1. In a TNF-α-induced in vivo inflammation model, at a dose of 10 mg/kg, RIPK1-IN-29 can protect mice from hypothermia and death. RIPK1-IN-29 can be applied to the research field of inflammatory diseases.
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- Formule: C16H17NO3S
- Masse moléculaire:303.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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RIPK1 6.9 nM (IC50) |
Chemical Information
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Masse moléculaire 303.38
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Formule C16H17NO3S
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SMILES
O=S(N1OCC[C@H]1C2=CC=CC=C2)(CC3=CC=CC=C3)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)